Multigeruza polimerikoak: mediku-protesietarako materialen ezaugarriak hobetzeko bidea

Abstract

There is a great demand for new materials in the field of biomedicine to be used as implants, however they cause rejection problems due to their lack of biocompatibility. In this work two substrates (inorganic and polymeric) will be surface modified using the layer by layer strategy (LbL), in order to construct hyaluronic and chitosan multilayers. It has been proven that the layers were successfully built by fluorescent confocal microscopy by means of the increase of fluorescence along layers deposition after fluorescent labelling of chitosan. Thanks to this, it has been possible to increase the hydrophilicity of the surfaces enhancing antibacterial properties and getting more biocompatible materials in a simple and inexpensive way.