Can microorganisms induce cancer?

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Published 25-11-2018
Aitana Arbizu Aitziber Antoran Idoia Buldain Aize Pellon Xabier Guruceaga Leire Martin-Souto Leire Aparicio Aitor Rementeria Fernando L. Hernando Andoni Ramirez-Garcia

Abstract

Many studies have analyzed relationships between microorganisms and cancer, demonstrating that microorganisms are able to prevent the onset of cancer and, others to provoke it. Specifically, more and more scientific articles are publishing on microorganisms, linking them to the creation, implementation and dispersion of cancer. In fact, it is estimated that microorganisms cause 17.8% of all cancers. The cancer-causing viral capability is the most studied and, in consequence, many different viral mechanisms that can cause cancer have been described. The International Cancer Research Institute has categorized eight viruses for the first time as "carcinogenic to humans", including a human papillomavirus, two herpesvirus and two hepatitis viruses. As regards bacteria, among cancerous agents, Helicobacter pylori is the most studied in relation to stomach cancer. In addition, many other bacteria, such as Salmonella typhi, Chlamydia pneumoniae and Streptococcus bovis, have been directly related to cancer. Although relatively little research on the effect of fungi on cancer has been investigated, some of the toxins produced by these microorganisms have been shown to cause cancer. In addition, some mechanism for the generation and spread of cancer have been described in Candida albicans. Studies to date have shown the influence of microorganisms on the development and promotion of cancer. For this reason, to face cancer in the next future, deepen into the relationship between cancer and microorganisms will be essential.

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Keywords

microbe, metastasis, cancer, infection, virus, bacterium, fungus

Section
Ale Arrunta