Mikrotxantiloien fabrikazioa eta hauen aplikazioak biomedikuntzan

Abstract

The use of biocompatible surfaces that allow selective adhesion of cells has gained tremendous interest in the biomedical field. Micropatterns, defined as surface shapes at the micrometric scale, are introduced as a versatile approach to obtain such surfaces that can promote controlled and directed cell growth in a specific substrate. Here, state of the art techniques found in bibliography to obtain micropatterned surfaces are thoroughly reviewed, together with their main applications in the field of biomedicine and tissue engineering such as biosensors, cell cultures for tissue engineering and/or suitable implant surfaces. Finally, some preliminary results obtained in our research group are presented herein, which highlight the potential of 3D printing  to achieve highly precise and accurate polymer micropatterns that promote selective cell adhesion.