Argiak zuzendutako tratamendu alternatiboa minbiziaren kontra

Abstract

One of the most noticeable concerns in society related with health is cancer owing to its high mortality rate. A great deal of research is conducted to treat cancer, find novel therapeutic treatments, and to avoid the harmful side effects of radiotherapy and chemotherapy in health. Nowadays, photodynamic therapy has arisen as a successful complementary alternative, mainly for skin diseases induced by cancer. In this light-driven method, a photosensitizer is required to generate singlet oxygen. Indeed, this last cytotoxic moiety shows anticarcinogenic activity.  The herein reported work is focused on photosensitizers. To this aim, we detail the molecular design to fulfill the required conditions, and explain the underlying photophysical phenomena behind the light-induced singlet oxygen generation. Finally, we report the state of the art regarding organic photosensitizers, with special interest in those based on BODIPY dyes.